pentobarbital will reduce the level or effect of itraconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.pentobarbital will decrease the extent or outcome of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the extent or impact of capivasertib by